Mervin Jules attended Baltimore City College in 1930 and received a degree from the Maryland Institute of Fine and Applied Arts in 1934. The following year he went to New York City and studied with Thomas Hart Benton at the Art Students League. Jules's work was first exhibited in 1935. He was artist-in-residence at Smith College from 1945 to 1946 and a professor from 1946 to 1969. In 1969 he became chairman of the art department at the City College of New York. In addition to teaching and exhibiting his work, Jules published articles about art. He had a studio in Provincetown, Massachusetts.